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KMID : 0191120130280010164
Journal of Korean Medical Science
2013 Volume.28 No. 1 p.164 ~ p.166
A Case of Hypersensitivity to Mosquito Bites without Peripheral Natural Killer Cell Lymphocytosis in a 6-Year-Old Korean Boy
Seon Han-Su

Roh Ji-Hyeon
Lee Seung-Ho
Kang Eun-Kyeong
Abstract
Hypersensitivity to mosquito bites (HMB) is a rare disease characterized by intense skin reactions such as bulla and necrotic ulcerations at bite sites, accompanied by general symptoms such as high-grade fever and malaise occurred after mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer (NK) cell leukemia/lymphoma. We describe here a Korean child who presented with 3-yr history of HMB without natural killer cell lymphocytosis. He has been ill for 6 yr with HMB. Close observation and examination for the development of lymphoproliferative status or hematologic malignant disorders is needed.
KEYWORD
Hypersensitivity, Mosquito Bites, Epstein-Barr Virus, Natural Killer Cell
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